This study was published on August 23, 2024, in European Journal of Preventive Cardiology.
This study aimed to prospectively investigate the association of smoking timing with risk of incident atrial fibrillation (AF).
A total of 305,627 participants with detailed information for time from waking to first cigarette were enrolled from UK Biobank database. Over a median 12.2-year follow-up, 13,410 AF cases were documented.
Compared to non-smokers, time from waking to the first cigarette showed gradient inverse associations with risk of incident AF (P-trend <0.001). The adjusted hazard ratio related to smoking timing was 1.13 (95% CI: 0.96-1.34) for >120 minutes, 1.20 (95% CI: 1.01-1.42) for 61-120 minutes, 1.34 (95% CI: 1.19-1.51) for 30-60 minutes, 1.43 (95% CI: 1.26-1.63) for 5-15 minutes, and 1.49 (95% CI: 1.24-1.63) for <5 minutes, respectively.
Although smoking is a well-known risk factor for AF. The increased risk of AF related to shorter time from waking to the first cigarette.
https://academic.oup.com/eurjpc/advance-article/doi/10.1093/eurjpc/zwae280/7738595?searchresult=1
