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The new European Cardiovascular Disease Risk Calculator is released

On June 13, 2021, the European Heart Journal published two papers dedicated to the development and validation of new European models for predicting cardiovascular risk in healthy people, which are called SCORE2 and SCORE2-OP and are expected to replace the currently used SCORE risk estimation charts. The first of these publications focuses on the model predicting a 10-year risk of fatal and non-fatal cardiovascular events in Europeans aged 40-69 with no previous cardiovascular disease (CVDs). The second paper looks at CVD risk assessment in CVD-free persons from older age groups (from 70 to 89 years old).

The SCORE2 model (for younger patients) is based on data from 45 cohorts in 13 countries (a total of 677,684 participants and 30,121 CVD events). For external validation, another 25 cohorts from 15 European countries were used (1,133,181 people, 43,492 events) were used. The SCORE2-OP risk charts for older age groups were developed based on a Norwegian cohort (28 503 people, 10 089 events), and for its external validation data from 338 615 participants from additional 6 cohorts (a total of 33 219 CVD events) were utilized.

Unlike the previous SCORE risk charts, the new models estimate risk of both cardiovascular mortality and non-fatal CVD events based on patients gender, age, smoking status, systolic blood pressure and non-HDL. The risk charts come in four versions for populations with low, moderate, high and very high CVD risk.

References:

1) https://academic.oup.com/eurheartj/advance-article/doi/10.1093/eurheartj/ehab309/6297709

2) https://academic.oup.com/eurheartj/advance-article/doi/10.1093/eurheartj/ehab312/6297711

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